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Main Functions

Core methods for network-based proteomic analysis

run_pkoi()
Run pKOI Network Enrichment Analysis
get_neighboring_nodes()
Get Neighboring Nodes in a Network

Data and Annotations

Annotation datasets used for node interpretation

pkoi_net
pkoi_net: Human-Specific Protein Knowledge Graph
anatomy_annotation
Anatomical Entity Annotations from UBERON
celltype_annotation
Cell Type Ontology Annotations (CL)
clinicallab_annotation
Clinical Laboratory Measurement Annotations (LOINC)
complex_annotation
Protein and Molecular Complex Annotations
compound_annotation
Chemical Compound Annotations
disease_annotation
Disease Ontology (DO) Annotations
ec_annotation
Enzyme Commission (EC) Number Annotations
go_annotation
Gene Ontology (GO) Term Annotations
mirna_annotation
Human miRNA Annotations (miRBase-style)
pathway_annotation
Pathway Annotations (WikiPathways)
protein_annotation
Protein Annotations (UniProt-Based)
proteindomain_annotation
Protein Domain Annotations (Pfam)
proteinfamily_annotation
Protein Family Annotations (Pfam Clans)
pwgroup_annotation
Pathway Group Annotations (Reactome Interaction Sets)
reaction_annotation
Biochemical Reaction Annotations (KEGG-Based)